The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425
Alternative Synonym:
NACAD, KIAA0363, NAC-alpha domain-containing protein 1
function:May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).,similarity:Belongs to the NAC-alpha family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
Western Blot analysis of Jurkat cells using NACAD Polyclonal Antibody
Western blot analysis of lysates from Jurkat cells, using NACAD Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using NACAD antibody.
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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