The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210
Alternative Synonym:
GALR1, GALNR, GALNR1, Galanin receptor type 1, GAL1-R, GALR-1
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],