The antiserum was produced against synthesized peptide derived from human NPHP4. AA range:877-926
Alternative Synonym:
NPHP4, KIAA0673, Nephrocystin-4, Nephroretinin
This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human brain, using NPHP4 Antibody. The picture on the right is blocked with the synthesized peptide.
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