The antiserum was produced against synthesized peptide derived from human AMPD1. AA range:261-310
Alternative Synonym:
AMPD1, AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using AMPD1 Antibody. The picture on the right is blocked with the synthesized peptide.
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