INPP5J rabbit pAb, Rabbit, Polyclonal
Artikelnummer:
EBT-ES5542
- Bilder (1)
| Artikelname: | INPP5J rabbit pAb, Rabbit, Polyclonal |
| Artikelnummer: | EBT-ES5542 |
| Hersteller Artikelnummer: | ES5542 |
| Alternativnummer: | EBT-ES5542-50, EBT-ES5542-100 |
| Hersteller: | ELK Biotechnology |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF, IHC |
| Spezies Reaktivität: | Human, Rat |
| Immunogen: | Synthesized peptide derived from INPP5J . at AA range: 850-930 |
| Alternative Synonym: | INPP5J, PIB5PA, PIPP, Phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A, Inositol polyphosphate 5-phosphatase J |
| catalytic activity:1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.,catalytic activity:D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-bisphosphate + phosphate.,domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.,function:Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.,PTM:Phosphorylated at Ser/Thr residues.,similarity:Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.,subcellular location:Predominantly localized to membrane ruffles., |
| Application Verdünnung: | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
|
|
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min). |
Produktgarantie und fachkundiger Support
