Cleaved-Integrin alpha5 HC (F42) rabbit pAb, Rabbit, Polyclonal
Artikelnummer:
EBT-ES5944
Hersteller Artikelnummer:
ES5944
Alternativnummer:
EBT-ES5944-50, EBT-ES5944-100
Hersteller:
ELK Biotechnology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
The antiserum was produced against synthesized peptide derived from human ITGA5. AA range:23-72
Alternative Synonym:
ITGA5, FNRA, Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e
integrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Western blot analysis of lysates from NIH/3T3 cells, treated with etoposide 25uM 24h, using ITGA5 (heavy chain,Cleaved-Phe42) Antibody. The lane on the right is blocked with the synthesized peptide.
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