A-Myb rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES6300
Artikelname: A-Myb rabbit pAb, Rabbit, Polyclonal
Artikelnummer: EBT-ES6300
Hersteller Artikelnummer: ES6300
Alternativnummer: EBT-ES6300-50, EBT-ES6300-100
Hersteller: ELK Biotechnology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human, Mouse
Immunogen: The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280
Alternative Synonym: MYBL1, AMYB, Myb-related protein A, A-Myb, Myb-like protein 1
function:Strong transcriptional activator, DNA-binding protein that specifically recognize the sequence 5-YAAC[GT]G-3. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,
Klonalität: Polyclonal
Konzentration: 1 mg/ml
Molekulargewicht: 85kD
NCBI: 4603
UniProt: P10243
Application Verdünnung: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Western blot analysis of lysates from LOVO cells, using MYB-A Antibody. The lane on the right is blocked with the synthesized peptide.