The antiserum was produced against synthesized peptide derived from human MYH4. AA range:1677-1726
Alternative Synonym:
MYH4, Myosin-4, Myosin heavy chain 2b, MyHC-2b, Myosin heavy chain 4, Myosin heavy chain IIb, MyHC-IIb, Myosin heavy chain, skeletal muscle, fetal
domain:The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.,function:Muscle contraction.,miscellaneous:Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Thick filaments of the myofibrils.,subunit:Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).,
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using MYH4 Antibody. The picture on the right is blocked with the synthesized peptide.
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