Trk A (phospho Tyr757) rabbit pAb, Rabbit, Polyclonal
Artikelnummer:
EBT-ES6424
Hersteller Artikelnummer:
ES6424
Alternativnummer:
EBT-ES6424-50, EBT-ES6424-100
Hersteller:
ELK Biotechnology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IF, IHC
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
The antiserum was produced against synthesized peptide derived from human Trk A around the phosphorylation site of Tyr757. AA range:726-775
Alternative Synonym:
NTRK1, MTC, TRK, TRKA, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A,
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk A (Phospho-Tyr757) Antibody. The picture on the right is blocked with the phospho peptide.
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