PLC beta2 rabbit pAb, Rabbit, Polyclonal

Artikelnummer: EBT-ES6603

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Artikelname:	PLC beta2 rabbit pAb, Rabbit, Polyclonal
Artikelnummer:	EBT-ES6603
Hersteller Artikelnummer:	ES6603
Alternativnummer:	EBT-ES6603-50, EBT-ES6603-100
Hersteller:	ELK Biotechnology
Wirt:	Rabbit
Kategorie:	Antikörper
Applikation:	IHC, WB
Spezies Reaktivität:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the Internal region of human PLC beta2.
Alternative Synonym:	PLCB2, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-2, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2

catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Binds 1 calcium ion per subunit.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,miscellaneous:The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with RAC1.,

Klonalität:	Polyclonal
Konzentration:	1 mg/ml
Molekulargewicht:	150kD
NCBI:	5330
UniProt:	Q00722

Application Verdünnung:

WB 1:500-2000,IHC-p 1:50-300

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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