The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310
Alternative Synonym:
POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A
DNA polymerase epsilon, catalytic subunit(POLE) Homo sapiens This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using POLE1 Antibody. The picture on the right is blocked with the synthesized peptide.
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