The antiserum was produced against synthesized peptide derived from human MUNC-18a around the phosphorylation site of Ser313. AA range:279-328
Alternative Synonym:
STXBP1, UNC18A, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Western blot analysis of lysates from COS7 cells treated with PMA 125ng/ml 30, using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right is blocked with the phospho peptide.
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