Ctip1 (6S12) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE09505
Artikelname: Ctip1 (6S12) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE09505
Hersteller Artikelnummer: AMRe09505
Alternativnummer: EKL-AMRE09505-50UL, EKL-AMRE09505-100UL, EKL-AMRE09505-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IHC, IP, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: EVI9, CTIP1, ZNF856, HBFQTL5, BCL11A-L, BCL11A-S, BCL11a-M, BCL11A-XL,
Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. Transcription factor (PubMed:16704730, PubMed:29606353). Associated with the BAF SWI/SNF chromatin remodeling complex (PubMed:23644491). Binds to the 5-TGACCA-3 sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene (PubMed:29606353). Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1, hence indirectly repressing fetal hemoglobin (HbF) level (PubMed:29606353, PubMed:26375765). Involved in brain development (PubMed:27453576). May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity). May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity).
Klonalität: Monoclonal
Molekulargewicht: 91kDa
NCBI: 53335
UniProt: Q9H165
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: BCL11A
Application Verdünnung: WB 1:2000-1:20000,IHC 1:50-1:200,ICC/IF 1:200-1:500,FC 1:100-1:200,IP 1:50-1:100



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