EAAT1 (14Y4) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE10263
Artikelname: EAAT1 (14Y4) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE10263
Hersteller Artikelnummer: AMRe10263
Alternativnummer: EKL-AMRE10263-50UL, EKL-AMRE10263-100UL, EKL-AMRE10263-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ICC, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: EA6, EAAT1, GLAST1, Slc1a3,
EAAT1 has neuroprotective potential following ischemia since reactive astrocytes and activated microglia express EAAT1 but not EAAT2. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport, this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).
Klonalität: Monoclonal
Molekulargewicht: 60kDa
NCBI: 6507
UniProt: P43003
Puffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: SLC1A3
Application Verdünnung: WB 1:1000-1:5000,IHC 1:50-1:500,ICC/IF 1:20-1:50



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