Enables cytoskeletal protein binding activity, protein deacetylase activity, and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation, protein deacetylation, and protein destabilization. Acts upstream of or within several processes, including aggresome assembly, cellular protein metabolic process, and neuron projection morphogenesis. Located in several cellular components, including dendrite, microtubule cytoskeleton, and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system, early embryo, future midbrain, gut gland, and lung. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Apr 2022]
