CD44 antibody, Unconjugated, Rabbit, Polyclonal
Artikelnummer:
GTX102111
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| Artikelname: | CD44 antibody, Unconjugated, Rabbit, Polyclonal |
| Artikelnummer: | GTX102111 |
| Hersteller Artikelnummer: | GTX102111 |
| Alternativnummer: | GTX102111-25, GTX102111-100 |
| Hersteller: | GeneTex |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ICC, IHC-Fr, IHC-P, IP, LCI, WB |
| Spezies Reaktivität: | Human, Rabbit, Rat |
| Immunogen: | Recombinant protein encompassing a sequence within the Extracellular domain of human CD44. The exact sequence is proprietary. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1 |
| CD44 is an 82kDa multifunctional transmembrane glycoprotein involved in cell migration, proliferation, differentiation, and signaling pathways that mediate cell survival. It is involved in many malignancies as well as being recognized as a cancer stem cell marker. Importantly, it is expressed in leukocytes and is a marker of leukemia-initiating cells, being found to be critical in the pathogenesis of T cell acute lymphoblastic leukemia. |
| Klonalität: | Polyclonal |
| Konzentration: | 0.5 mg/ml (Please refer to the vial label for the specific concentration.) |
| Molekulargewicht: | 82 |
| Sensitivitaet: | IP/MS validation is based on published data (PMID: 30377381). |
| NCBI: | 960 |
| UniProt: | P16070 |
| Puffer: | PBS, 20% Glycerol, 0.025% ProClin 300. |
| Formulierung: | Liquid |
| Anwendungsbeschreibung: | WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
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