Azemiglitazone potassium (MSDC-0602K), a PPARgamma-sparing thiazolidinedione (Ps-TZD), binds to PPARgamma with the IC50 of 18.25 µM[1]. Azemiglitazone potassium modulates the mitochondrial pyruvate carrier (MPC). Azemiglitazone potassium can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance[2]. Azemiglitazone potassium, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide[3].
Molekulargewicht:
409.50
Reinheit:
98.94
CAS Nummer:
[1314533-27-1]
Formel:
C19H16KNO5S
Target-Kategorie:
Insulin Receptor,PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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