LDN193189 GMP is LDN193189 (HY-12071) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3][4][5].
Molekulargewicht:
406.49
CAS Nummer:
[1062368-24-4]
Formel:
C25H22N6
Target-Kategorie:
Organoid,TGF-beta Receptor
Anwendungsbeschreibung:
MCE Product type: GMP Small Molecules
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