PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.
Molekulargewicht:
647.72
CAS Nummer:
[320347-28-2]
Formel:
C29H45N9O8
Target-Kategorie:
Protease Activated Receptor (PAR)
Anwendungsbeschreibung:
MCE Product type: Peptides
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