This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of Colon lysate using CEA Mouse Monoclonal Antibody (CEACAM5/12673).
SDS-PAGE Analysis of Purified CEA Mouse Monoclonal Antibody(CEACAM5/173 ). Confirmation of Purity and Integrity of Antibody.
SDS-PAGE Analysis of Purified CEA Mouse Monoclonal Antibody(CEACAM5/12673). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of Human intestine, Mouse intestine, Rat intestine, Hamster intestine, Guinea pig intestine and Rabbit intestine tissue lysates using CEACAM5 Mouse Monoclonal Antibody (CEACAM5/12673).
Formalin-fixed, paraffin-embedded human colon stained with CEA Mouse Monoclonal Antibody (CEACAM5/12673). Inset: PBS instead of primary antibody, secondary only negative control.
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