Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of RH-30 cell lysate using CTNNB1 Mouse Monoclonal Antibody (CTNNB1/7760).
Formalin-fixed, paraffin-embedded human pancreas stained with Beta-Catenin Mouse Monoclonal Antibody (CTNNB1/7760). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified Beta-Catenin Mouse Monoclonal (CTNNB1/7760). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of RH-30 cell lysate using Beta-Catenin Mouse Monoclonal Antibody (CTNNB1/7760).
Analysis of Protein Array containing more than 19,000 full-length human proteins using Beta-Catenin Mouse Monoclonal Antibody (CTNNB1/7760). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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