Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody, IgG1, Clone: [ELN/2069], Mouse, Monoclonal
Artikelnummer:
NBT-2006-MSM2-P1ABX
Hersteller Artikelnummer:
2006-MSM2-P1ABX
Alternativnummer:
NBT-2006-MSM2-P1ABX-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
ELISA, IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant full-length human Elastin protein
Alternative Synonym:
Elastin, ELN, SVAS, Tropoelastin, WBS, WS
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
ELISA (For coating, order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling
Formalin-fixed, paraffin-embedd
Formalin-fixed, paraffin-embedded human Pancreas stained with Elastin Mouse Monoclonal Antibody (ELN/2069).
Formalin-fixed, paraffin-embedded human Small Intestine stained with Elastin Mouse Monoclonal Antibody (ELN/2069).
Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Elastin Mouse Monoclonal Antibody (ELN/2069).
SDS-PAGE Analysis of Purified Elastin Mouse Monoclonal Antibody (ELN/2069). Confirmation of Integrity and Purity of Antibody.
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