Activated leukocyte cell adhesion molecule (ALCAM), expressed on activated leukocytes, T cells, B cells and monocytes, is a member of the immunoglobulin superfamily (IgSF) and identified as a CD6 ligand. CD6 is a type I membrane protein in the scavenger receptor cysteine rich protein superfamily that acts in T cell adhesion and costimulation. ALCAM mediates thymocyte-thymic epithelial cell adhesion via homophilic (ALCAM-ALCAM) and heterophilic (ALCAM-CD6) interactions involving a previously undescribed protein-protein interaction between a member of the scavenger receptor cysteine rich protein superfamily and the immunoglobulin superfamily.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Albumin Mouse Monoclonal Antibody (ALB/2144).
SDS-PAGE Analysis of Purified Albumin Mouse Monoclonal Antibody (ALB/2144). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Albumin Mouse Monoclonal Antibody (ALB/2144). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD,Aövivs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD,Aövivs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
Western Blot Analysis Albumin of human liver tissue lysate using Albumin Mouse Monoclonal Antibody (ALB/2144).
Western blot analyses of A-549 and A-431 cell lysates using CD166 Recombinant Mouse Monoclonal Antibody (rMOG/07).
Formalin-fixed, paraffin-embedded human parathyroid gland stained with ALCAM / CD166 Recombinant Mouse Monoclonal Antibody (rMOG/07). Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified ALCAM / CD166 Recombinant Mouse Monoclonal Antibody (rMOG/07). Confirmation of Purity and Integrity of Antibody.
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