The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western blot analysis of human small intestine tissue lysate using FABP2 Mouse Monoclonal Antibody (FABP2/6345).
Western blot analysis of Human Intestine, Mouse Intestine and Rat Intestine tissue lysates using FABP2 Mouse Monoclonal Antibody (FABP2/6345).
Western blot analysis of human small intestine tissue lysate using FABP2 (Marker of Metastatic Potential in Colorectal Cancer) Mouse Monoclonal Antibody (FABP2/6345).
Analysis of Protein Array containing more than 19,000 full-length human proteins using FABP2 Mouse Monoclonal Antibody (FABP2/6345). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Formalin-fixed, paraffin-embedded human kidney stained with FABP2 Mouse Monoclonal Antibody (FABP2/6345). Inset: PBS instead of primary antibody, secondary only negative control.
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