FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Antibody, IgG2a, Clone: [FABP5/3750], Mouse, Monoclonal
Artikelnummer:
NBT-2171-MSM2-P1
Hersteller Artikelnummer:
2171-MSM2-P1
Alternativnummer:
NBT-2171-MSM2-P1-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant full-length human FABP5 protein
Alternative Synonym:
FABP5, E-FABP, EFABP, PA-FABP, PAFABP
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis o
Formalin-fixed, paraffin-embedded human Liver tissue stained with FABP5 Mouse Monoclonal Antibody (FABP5/3750).
SDS-PAGE Analysis Purified FABP5 Mouse Monoclonal Antibody (FABP5/3750). Confirmation of Purity and Integrity of Antibody.
SDS-PAGE Analysis of Purified FABP5 Mouse Monoclonal Antibody (FABP5/3750). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using FABP5 Mouse Monoclonal Antibody (FABP5/3750). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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