Recombinant Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) Antibody, Clone: [AKR1B1/7010R], Rabbit, Monoclonal
Artikelnummer:
NBT-231-RBM4-P0
Hersteller Artikelnummer:
231-RBM4-P0
Alternativnummer:
NBT-231-RBM4-P0-20,NBT-231-RBM4-P0-100
Hersteller:
NeoBiotechnologies
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant human full-length AKR1B1 protein
Alternative Synonym:
AKR1B1, Aldehyde reductase, aldehyde reductase 1, Aldo-keto reductase family 1 member B1, aldo-keto reductase family 1, member B1 (aldose reductase), Aldose reductase, AR, Lii5-2 CTCL tumor antigen, low Km aldose reductase
AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Anwendungsbeschreibung:
Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 2
IHC analysis of formalin-fixed, paraffin-embedded human
IHC analysis of formalin-fixed, paraffin-embedded human brain. Staining using AKR1B1/7010R at 2ug/ml in PBS for 30min RT. Inset: PBS instead of primary antibody, secondary only negative control.
SDS-PAGE Analysis of Purified AKR1B1 Rabbit Monoclonal Antibody (AKR1B1/7010R). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of HEK293T lysate using AKR1B1 Rabbit Monoclonal Antibody (AKR1B1/7010R).
Western blot analysis of HEK293T lysate using AKR1B1 Rabbit Monoclonal Antibody (AKR1B1/7010R).
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