Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
Alternative Synonym:
Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Anwendungsbeschreibung:
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 mi
Formalin-fixed, paraffin-embedded human Pancreas stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1388).
Formalin-fixed, paraffin-embedded human Pancreas stained with Ferritin, Light Chain Recombinant Mouse Monoclonal Antibody (rFTL/1388).
SDS-PAGE Analysis of Purified Ferritin LC Recombinant Mouse Monoclonal Antibody (rFTL/1388). Confirmation of Integrity and Purity of Antibody
Western Blot Analysis of human Kidney tissue lysate using Ferritin LC Recombinant Mouse Monoclonal Antibody (rFTL/1388).
Western blot analysis of Brain, Kidney, Liver, Lung and Spleen tissue lysates of human using FTL Recombinant Mouse Monoclonal Antibody (rFTL/1388).
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