Ep-CAM / CD326 (Cytoplasmic Domain) (Epithelial Marker) Antibody, IgG2b, Clone: [EGP40/1110], Mouse, Monoclonal

Artikelnummer: NBT-4072-MSM10-P0
Artikelname: Ep-CAM / CD326 (Cytoplasmic Domain) (Epithelial Marker) Antibody, IgG2b, Clone: [EGP40/1110], Mouse, Monoclonal
Artikelnummer: NBT-4072-MSM10-P0
Hersteller Artikelnummer: 4072-MSM10-P0
Alternativnummer: NBT-4072-MSM10-P0-20,NBT-4072-MSM10-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Canine, Feline, Human
Immunogen: Recombinant fragment from cytoplasmic domain (around aa 289-314) of human EpCAM (exact sequence is proprietary)
Alternative Synonym: Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, EGP2, EGP314, EGP40, Epithelial Cell Adhesion Molecule, Epithelial Glycoprotein 314, ESA, KSA, TACD1, TROP1, Tumor-associated Calcium Signal Transducer 1 (TACSTD1), ECS-1, Epidermal Surface Antigen 1, ESA1, FLOT2, Flotillin-2, Membrane Component, Chromosome 17, Surface Marker-1 (M17S1), REG-1, Reggie-1, Reggie-2
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Klonalität: Monoclonal
Klon-Bezeichnung: [EGP40/1110]
Molekulargewicht: 40-43kDa
Isotyp: IgG2b
NCBI: 4072
UniProt: P16422
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti
Formalin-fixed, paraffin-embeddedhuman ovarian carcinoma stained with EpCAM Mouse Monoclonal Antibody (EGP40/1110).
Formalin-fixed, paraffin-embedded rat oviduct stained with EpCAM Mouse Monoclonal Antibody (EGP40/1110).
Formalin-fixed, paraffin-embedded rat colon stained with EpCAM Mouse Monoclonal Antibody (EGP40/1110).
Formalin-fixed, paraffin-embedded rat lung stained with EpCAM Mouse Monoclonal Antibody (EGP40/1110).
Formalin-fixed, paraffin-embedded mouse colon stained with EpCAM Mouse Monoclonal Antibody (EGP40/1110).
SDS-PAGE Analysis Purified EpCAM Mouse Monoclonal Antibody (EGP40/1110). Confirmation of Purity and Integrity of Antibody.