It is a cocktail of four highly specific monoclonal antibodies that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (EpCAM). It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or EpCAM. EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
200ug/ml of Abs purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot analysis of human lung tissue lysate using EpCAM Mouse Monoclonal Antibody (PAN-EpCAM).
SDS-PAGE Analysis of Purified EpCAM Mo
Formalin-fixed, paraffin-embedded human breast carcinoma stained with EpCAM Mouse Monoclonal Antibody (PAN-EpCAM).
Western Blot analysis of human lung tissue lysate using EpCAM Mouse Monoclonal Antibody (PAN-EpCAM).
SDS-PAGE Analysis of Purified EpCAM Mouse Monoclonal Antibody (PAN-EpCAM). Confirmation of Integrity and Purity of Antibody
Flow Cytometric Analysis of PFA-fixed MCF-7 cells using EpCAM Mouse Monoclonal Antibody (PAN-EpCAM) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).
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