CDC47, DNA replication licensing factor MCM7, MCM7 mini chromosome maintenance deficient 7, Mini chromosome Maintenance 7, Mini chromosome maintenance protein 7, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Anwendungsbeschreibung:
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 min
Formalin-fixed, paraffin-embedded human Tonsil stained with MCM7 Recombinant Rabbit Monoclonal Antibody (MCM7/2756R).
Western Blot Analysis of MCF-7, HEK-293, A549, SKBr3, HeP2 lysate using MCM7 Mouse Monoclonal Antibody (MCM7/2756R).
Western Blot Analysis of A-431, A549 and HEK293T lysates using MCM7 Rabbit Recombinant Monoclonal Antibody (MCM7/2756R).
Western Blot Analysis of Human Skin and HEK293 lysates using MCM7 Rabbit Recombinant Monoclonal Antibody (MCM7/2756R).
SDS-PAGE Analysis of Purified MCM7 Recombinant Rabbit Monoclonal Antibody (MCM7/2756R). Confirmation of Purity and Integrity of Antibody.
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