A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Alternative Synonym:
Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, Bax protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform gamma, Bax zeta, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, BCL2L4
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Hodgkin&apos,s Lymphoma stained with Bax Mouse Monoclonal Antibody (2D2).
Flow Cytometric Analysis of human Jurkat cells using Bax Mouse Monoclonal Antibody (2D2) followed by Goat anti-Mouse IgG-CF488 (Orange), cells alone (Blue), Isotype Control (Red).
Confocal Immunofluorescence of Human Jurkat cells A. Bax Mouse Monoclonal Antibody (Clone 2D2) B. Goat anti Mouse CF488. labeled with CF488 (Green), Reddot is used to label the nuclei.
SDS-PAGE Analysis of Purified Bax Mouse Monoclonal Antibody (2D2). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of A-549 lysate using Bax Mouse Monoclonal Antibody (2D2).
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