Recombinant Spectrin Alpha 1 (Erythrocyte Marker) Antibody, IgG1, Clone: [rSPTA1/1832], Mouse, Monoclonal

Artikelnummer: NBT-6708-MSM4-P0
Artikelname: Recombinant Spectrin Alpha 1 (Erythrocyte Marker) Antibody, IgG1, Clone: [rSPTA1/1832], Mouse, Monoclonal
Artikelnummer: NBT-6708-MSM4-P0
Hersteller Artikelnummer: 6708-MSM4-P0
Alternativnummer: NBT-6708-MSM4-P0-20,NBT-6708-MSM4-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant fragment of human SPTA (around aa356-475) (exact sequence is proprietary)
Alternative Synonym: Alpha I spectrin, Elliptocytosis 2 (EL2), Erythrocyte alpha spectrin, Erythroid alpha-spectrin, HPP, HS3, Spectrin alpha erythrocytic 1, SPH3, SPTA1
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
Klonalität: Monoclonal
Klon-Bezeichnung: [rSPTA1/1832]
Molekulargewicht: 240kDa
Isotyp: IgG1
NCBI: 6708
UniProt: P02549
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Western Blot (1-2ug/ml),Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 min
Formalin-fixed, paraffin-embedded human Placenta stained with Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1832).
SDS-PAGE Analysis Purified Spectrin alpha 1 Mouse Recombinant Monoclonal (rSPTA1/1832). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of human K562 cell lysate using Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1832).
Western Blot Analysis of human HeLa cell lysate using Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1832).
Formalin-fixed, paraffin-embedded human Placenta stained with Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1832).
Western Blot Analysis of human Kidney, Human Lung and K-562 lysates using Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1832).