CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Flow Cytometry (1-2ug/ml), ,Immunofluorescence (1-2ug/ml), ,Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified CD6 Mouse Monoclonal Antibody (SPV-L14).
Immunofluorescence staining of M
SDS-PAGE Analysis of Purified CD6 Mouse Monoclonal Antibody (SPV-L14).
Flow Cytometric Analysis of MOLT-4 cells. CD6 Mouse Monoclonal Antibody (SPV-L14) followed by Goat anti-Mouse IgG-CF488 (Blue), Isotype control (Red).
Immunofluorescence staining of MOLT4 cells using CD6 Mouse Monoclonal Antibody (SPV-L14) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are stained with Reddot.
Western Blot Analysis of Human Spleen, Jurkat, Raji, MCF7, and PBMC lysates using CD5 Mouse Monoclonal Antibody (SPV-L14).
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
