A portion of amino acids 31-61 from the human protein was used as the immunogen for this TrkC antibody.
Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. [UniProt]
The stated application concentrations are suggested starting amounts. Titration of the TrkC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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