MST1 Antibody (Mammalian STE20-like protein kinase 1), Rabbit, Polyclonal
Artikelnummer:
NSJ-F50888-0.08ML
Hersteller Artikelnummer:
F50888-0.08ML
Alternativnummer:
NSJ-F50888-0.08ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IHC, WB
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.
MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
