CFP Antibody / Complement Factor P / Properdin, Rabbit, Polyclonal
Artikelnummer:
NSJ-F52012-0.4ML
Hersteller Artikelnummer:
F52012-0.4ML
Alternativnummer:
NSJ-F52012-0.4ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, FACS, WB
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
