SUZ12 Antibody / Suppressor of zeste 12 protein homolog, Rabbit, Polyclonal
Artikelnummer:
NSJ-F52128-0.08ML
Hersteller Artikelnummer:
F52128-0.08ML
Alternativnummer:
NSJ-F52128-0.08ML
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, WB
Spezies Reaktivität:
Human, Mouse
Immunogen:
A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody.
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.