TICAM1 Antibody, Rabbit, Polyclonal

Artikelnummer: NSJ-F52327-0.4ML
Artikelname: TICAM1 Antibody, Rabbit, Polyclonal
Artikelnummer: NSJ-F52327-0.4ML
Hersteller Artikelnummer: F52327-0.4ML
Alternativnummer: NSJ-F52327-0.4ML
Hersteller: NSJ Bioreagents
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human, Mouse
Immunogen: A portion of amino acids 115-143 from the human protein was used as the immunogen for this TICAM1 antibody.
Involved in innate immunity against invading pathogens. Adapter used byTLR3andTLR4(through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteinsTBK1, TRAF6 andRIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7,NF-kappa-Band FADD respectively.
Klonalität: Polyclonal
UniProt: Q8IUC6
Reinheit: Antigen affinity
Formulierung: In 1X PBS, pH 7.4, with 0.09% sodium azide
Antibody Type: Primary Antibody
Application Verdünnung: Western blot: 1:1000
Anwendungsbeschreibung: Titration of the TICAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
623,00 €
0.4 ml
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