This Kdm6b antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1023-1057 amino acids from mouse Kdm6b.
Histone demethylase that specifically demethylates Lys- 27 of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 Lys-27. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
