This POU5F1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 291-324 amino acids from the C-terminal region of human POU5F1.
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
