This anti-CD34 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the C-terminal region of human CD34.
CD34 is a possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
