This Notch1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2403-2437 amino acids from the C-terminal region of mouse Notch1.
Notch1 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. It is involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. [UniProt]
