A portion of amino acids 9-33 from the human protein was used as the immunogen for the MAP1LC3B antibody.
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
The stated application concentrations are suggested starting points. Titration of the MAP1LC3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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