A portion of amino acids 303-346 from the human protein was used as the immunogen for the STRADA antibody.
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:25,Immunofluorescence: 1:25,Flow cytometry: 1:25 (1x10e6 cells)
Anwendungsbeschreibung:
The stated application concentrations are suggested starting points. Titration of the STRADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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