Recombinant IgM Heavy Chain Antibody, Clone: [IGHM/3803R], Rabbit, Monoclonal
Artikelnummer:
NSJ-V8052SAF-100UG
Hersteller Artikelnummer:
V8052SAF-100UG
Alternativnummer:
NSJ-V8052SAF-100UG
Hersteller:
NSJ Bioreagents
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC-P
Spezies Reaktivität:
Human
Immunogen:
Full length recombinant human IGHM protein was used as the immunogen for the recombinant IgM antibody.
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.