IL-10RA Antibody / IL-10R1, Clone: [1B1.3a], Rat, Monoclonal
Artikelnummer:
NSJ-V8346-100UG
Hersteller Artikelnummer:
V8346-100UG
Alternativnummer:
NSJ-V8346-100UG
Hersteller:
NSJ Bioreagents
Wirt:
Rat
Kategorie:
Antikörper
Applikation:
FACS
Spezies Reaktivität:
Mouse
Immunogen:
Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.
This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
