Apolipoprotein B Antibody / APOB, Clone: [APOB/4333], Mouse, Monoclonal
Artikelnummer:
NSJ-V8609-100UG
Hersteller Artikelnummer:
V8609-100UG
Alternativnummer:
NSJ-V8609-100UG
Hersteller:
NSJ Bioreagents
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC-P
Spezies Reaktivität:
Human
Immunogen:
A portion of amino acids 592-689 from the human protein was used as the immunogen for the Apolipoprotein B antibody.
Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the resultof RNA editing of a common apoB gene.
