Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant TMEPAI antibody.
PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[PMEPA1/6421R]
UniProt:
Q96W9
Reinheit:
Protein A/G affinity
Formulierung:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Antibody Type:
Primary Antibody
Application Verdünnung:
Immunohistochemistry (FFPE): 1-2ug/ml
Anwendungsbeschreibung:
Optimal dilution of the recombinant TMEPAI antibody should be determined by the researcher.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
