Recombinant TMEPAI Antibody / PMEPA1, Clone: [PMEPA1/6421R], Rabbit, Monoclonal

Artikelnummer: NSJ-V9209SAF-100UG
Artikelname: Recombinant TMEPAI Antibody / PMEPA1, Clone: [PMEPA1/6421R], Rabbit, Monoclonal
Artikelnummer: NSJ-V9209SAF-100UG
Hersteller Artikelnummer: V9209SAF-100UG
Alternativnummer: NSJ-V9209SAF-100UG
Hersteller: NSJ Bioreagents
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC-P
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant TMEPAI antibody.
PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Klonalität: Monoclonal
Klon-Bezeichnung: [PMEPA1/6421R]
UniProt: Q96W9
Reinheit: Protein A/G affinity
Formulierung: 1 mg/ml in 1X PBS, BSA free, sodium azide free
Antibody Type: Primary Antibody
Application Verdünnung: Immunohistochemistry (FFPE): 1-2ug/ml
Anwendungsbeschreibung: Optimal dilution of the recombinant TMEPAI antibody should be determined by the researcher.