WM165 is a metastatic human melanoma cell line that displays fibroblastic morphology. This cell line was derived from the same patient as the cell lines WM115, WM239A, and WM266-4. WM115 cell line originated from the primary tumor, and WM266-4, WM165-1 and WM239A were from individual lymph-node metastases. This cell line expresses mutant BRAF (V600D), PTEN loss of function including hemizygous deletion, and wild type N-RAS, c-KIT, and CDK4. WM165 cells produce xenograft tumors when injected into immunocompromised mice.
Konzentration:
1.0 million cells/mL (Count By Hemocytometer)
Puffer:
None
Quelle:
Human
Formulierung:
Frozen Cell Suspension
Anwendungsbeschreibung:
The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways.
Human melanoma tumor cells with known gene mutations, disease stage, STR, and RPPA profiling
Established WM165-1 viable cell growth in culture using appropriate Tumor Specialized Media with 2%FBS.
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